The short answer is: Yes.
45 ACP uses lead .451 and jacketed .452. 45 LC is the opposite, it uses jacketed .451 and lead .452. In my experience, you can load the bullets interchangeably. When in doubt, slug your barrel - this should calm your concerns.
The two main reason for fowling in lead is higher speed loads or soft lead. If you keep your speed around 850fps in a 45ACP, lead fowling shouldn't be much of an issue. A 45LC lead load should only be <100-150fps faster than this, so you should be good. If you really want clean loads, shoot copper plated bullets. They're cheap, and at these velocities, they'll be completely intact when they hit the target.