It has never been a good idea to frequently unload and reload the same round in a semi-auto. A buddy sent this link to me: Officer Safety: Ammunition cycling and failure to fire « The Bolo Report
A more practical method of home storage is probably to use a trigger lock or a locked storage box.
The thread discusses bullet setback, which can be checked visually using tools, but this primer problem is new to me. I would think that maybe a good precaution for someone who unloads the chamber daily and reloads it would be to keep that old round for practice and put in a fresh round each day. That would be pretty expensive though. When I daily carried a semi-auto pistol, I would leave it loaded, but my children were trained and older. If I had small kids, I would probably leave my pistol loaded and left in a safe of some kind. I leave a few guns loaded in my safe to this day.Check out this thread where it was discussed in a little more detail:
https://www.indianagunowners.com/fo...an_i_chamber_the_top_round_in_a_semiauto.html