My hunting load for years has been 200gr Hornady XTP with 24.5 grs Hodgdon H110. Very accurate in both my Super Blackhawks and my son's Redhawk. Ab Every deer I have hit with this load have fallen within sight of my stand, with one large doe dropping in her tracks. When I opened up her chest cavity it looked like a bomb had gone off inside her. Farthest shot I have taken on deer with this load has been about 35 yards, but am able to knock down bowling pins out to 100 yards.