I use spp with 2400 in my 357 loads, never been a problem.
It's generally not a problem to use magnum primers in place of standard ones as long as you work up your load with them.
You can run into problems if you substitute a magnum primer for a standard in a load that's at or near max.
Handloader, (or maybe Rifle), did a write about it a year or so back. They got some pretty significant differences when they used a magnum primer in place of a standard in a near max load.
Depending on where you are at with your Titegroup load, a magnum primer might create an over pressure issue. I have read to reduce your load by 10% when using magnum primers and then work up from there.
90% of all my reloading is done with Titegroup. I have never needed a magnum primer to ignite it.
I use mag primers in all my .357 loads. I had a shop owner say that W296 was a junk powder because it only ignited half the time which didn't make sense to me at the time because I never had any issues, but after reading an article in Handloader W296/H110 require them. He was so used to using 2400 so I'm sure it never crossed his mind that you would need anything other than a regular primer.