I like the idea of throwing a different upper on my rifle and hitting the woods. It seem logical and cost effective a 300 blk out suppressed would be both quiet and really manageable. Shot placement aside its really a case of each their own. I flirted with the idea of canning the 30/30. I hate earpro and have lost enough already. A can seems super logical. In many countries they used quite often. It's just part of the evolution of hunting.
I see shooting something like a coyote with a subsonic while in your stand beneficial as it won't spook deer in the distance. However, even out of a short 8-10" barrel 300blk supers or more than plesant to the ear. I don't see any reason to hunt with subs over them.